This is the combination of FLUTICASONE FUROATE AND AZELASTIN NASAL SPRAY
There is a confusion between Fluticasone Furoate and Fluticasone Propionate but this confusion clearly stems from the unusual assigned glucocorticoid nomenclature which splits these molecules into the steroidal backbone (fluticasone) and the ester substituent (furoate/propionate). This naming convention does suggest that these derivatives could be ester prodrugs of fluticasone. In fact, a number of topical glucocorticoid esters are indeed ester prodrugs releasing the active parent glucocorticoid in the body. However, fluticasone are remarkably stable and remain attached to the fluticasone backbone even during metabolism. Their pharmacological activity is mediated by the entire molecule (backbone + ester) and they share no common metabolites neither FF nor FP is metabolised to fluticasone. FF and FP are therefore structurally distinct drug substances with distinct properties.